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Artículo Tomo 71, Número. 4, Mayo 2018

Archivos Españoles de Urología

Heat-targeted drug delivery: A promising approach for organsparing treatment of bladder cancer. THERMODOX«

Authors: Alireza Aminsharifi, Steven C. Brousell, Andrew Chang, Juan Leˇn y Brant A. Inman.

Arch. Esp. Urol. 2018; 71 (4): 447-452

Vol. 71, Number. 4, May 2018

Disease recurrence and progression remain as significant challenges for the management of non-muscle invasive bladder cancer (NMIBC). In recent years, novel drugs and delivery systems have been investigated as strategies to reduce recurrence, progression and mortality. In this review, we focus on the role of intravesical hyperthermic chemotherapy and discuss a novel approach involving a heat-activated drug delivery system (ThermoDox«) that enables local accumulation of systemic chemotherapy.

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