Recurrent urinary tract infections: prevention of recurrence with intravesical instillations
of chondroitin sulfate and hyaluronic acid.Authors:
Jesús Ignacio Tornero Ruiz, Gloria Martínez Gómez, José Félix Escudero Bregante y Guillermo Antonio Gómez Gómez.
Arch. Esp. Urol. 2017; 70 (2): 288-293
Vol. 70, Number. 2, March 2017
OBJECTIVE: The aim of our study is to
demonstrate that intravesical administration of the
association chondroitin sulfate (CS) and hyaluronic acid
(HA), according to our treatment schedule, is a benefit
for women with recurrent urinary tract infections (RUTI),
not only from a clinical point of view, but also reducing
METHODS: This is a study of 28 women diagnosed with
RUTI, with a positive culture, and compatible symptoms; frethey
underwent treatment according to the protocol of
intravesical instillations of the combination CS 2%-1 gr +
HA 1.6%-800 mg.
To evaluate the effectiveness of the treatment, symptoms
improvement, reduction of the number of episodes of
urinary tract infection and quality of life were considered.
RESULTS: In our series, we can observe an improvement
of the quality of life assessed by PG-I, 66% after 12
months. It was seen that 55.6% of the patient`s urine
cultures became negative, while 44.4% had episodes
of urinary infection, but with lower baseline symptoms
DISCUSSION: Patients included in the protocol of
instillation improved significantly their quality of life; in
addition, to a considerable extent new urinary infections
were not presented, being milder when they presented.
ONLY IN SPANISH.